DOCUMENTED RESULTS

Clinical Outcomes

What Dante found. What happened next.

The cases on this page are documented clinical outcomes. Each describes what a patient presented with, what Dante WGS identified, and what clinical action followed.

NOONAN SYNDROME + RUNX1 DEFICIENCY · NHS GENETICS · QUEEN ELIZABETH UNIVERSITY HOSPITAL GLASGOW

Thomas's Story

Thomas spent years under investigation for a constellation of symptoms no specialist had been able to connect. Standard diagnostic pathways were inconclusive. Traditional genetic panels returned nothing actionable.

Dante Whole Genome Sequencing identified two findings: genetic variants consistent with Noonan Syndrome and a rare RUNX1 deficiency, a variant associated with a hereditary predisposition to leukemia. These two findings, taken together, explained the clinical picture that had eluded his medical team for years.

The Dante Labs report was reviewed and accepted by NHS genetics at Queen Elizabeth University Hospital Glasgow. Clinical management was updated based on the findings.

format_quote

"They never added the numbers up until now when they saw the Dante Labs report."

TS

Thomas, Scotland

Queen Elizabeth University Hospital Glasgow, NHS

IMMUNE DISORDER · CLINICAL INSTITUTION PENDING CONFIRMATION · DUBAI

Ahmed's Story

Ahmed was three years old when his family sought answers for a suspected immune disorder. Traditional testing had not identified a genetic cause.

Dante Whole Genome Sequencing identified genetic variants associated with an immune disorder. The findings were reviewed by clinical teams in Dubai, who are evaluating the results in the context of Ahmed's care.

CASE STATUS

Pending confirmation

Patient Ahmed, age 3
Location Dubai
Finding Immune disorder variants
Method Dante WGS

BRUGADA SYNDROME · SCN5A VARIANT · HEREDITARY CARDIAC CASCADE

Hereditary Cardiac Risk Identified

A family member underwent Dante Whole Genome Sequencing and was found to carry an SCN5A variant associated with Brugada syndrome, a hereditary cardiac condition that can cause sudden cardiac arrest.

The identification of this variant initiated cascade genetic testing across the family, allowing at-risk relatives to be identified and monitored before a cardiac event occurs.

CASE STATUS

Pending confirmation

Condition Brugada syndrome
Variant SCN5A
Action Cascade family testing
Method Dante WGS

VERIFIED PRODUCTION FIGURES

Across 100 Countries

1.3M+

genomic reports delivered

4.6–5M

variants per genome

99.98%

sequencing accuracy

~22%

new findings within 3 years

ACCREDITATIONS

Clinical Credentials

verified

CLIA Certified

Clinical Laboratory Improvement Amendments. Required for any laboratory performing testing on human specimens for clinical purposes in the United States.

verified

ISO 15189 Accredited

International standard for medical laboratory quality and competence. Recognized globally as the benchmark for clinical laboratory operations.

verified

ISO 9001 Certified

Quality management systems standard. Demonstrates consistent quality control processes across all laboratory and production operations.

verified

ISO 13485 Certified

Medical devices quality management standard. Applies to the design, production, and servicing of medical devices and related services.

local_hospital

NHS-Accepted

Dante Labs results have been reviewed and accepted by NHS clinical genetics teams for diagnostic and care management decisions.

lock

GDPR Compliant

Full compliance with the EU General Data Protection Regulation. Data processed in EU jurisdiction. Your genomic data is never sold or used for advertising.

Your genome has answers. Get them.

Clinical-grade whole genome sequencing. 30X coverage. 200+ physician-ready reports. Results in 6 to 8 weeks.